Cancer3.AIAI in OncologyAI Models › Datasets

AI in Oncology · AI Models

A researcher-grade catalog of AI models, datasets and open data needs in oncology — every card structured, sourced and dated.

Datasets, registries and benchmarks you can train or evaluate oncology models on — with access conditions, licences, sizes, annotations and the models already using them. { } export JSON

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AACR Project GENIE

American Association for Cancer Research; hosted on Synapse / cBioPortal
Registry / portal Free registration AACR GENIE data-use terms (Synapse registration)

The largest real-world clinical sequencing registry in oncology — the place to test whether a variant-effect or biomarker model generalises beyond TCGA.

200 000 patients clinical-grade tumour sequencing from 19+ institutions with limited clinical data; releases twice a year

CPTAC — Clinical Proteomic Tumor Analysis Consortium

NCI Office of Cancer Clinical Proteomics Research
Registry / portal Free registration open (proteomics via PDC) / controlled (raw sequencing via dbGaP)

Proteogenomic companion to TCGA: the largest public set where protein-level measurements, genomics and images exist for the same tumours.

1 000 patients 10+ tumour types with proteogenomic profiling (proteome, phosphoproteome) on genomically characterised cases; images in TCIA
Dataset site used by models: 2 Open card →

TCGA — The Cancer Genome Atlas (via NCI Genomic Data Commons)

NCI / NHGRI; hosted by the Genomic Data Commons
Registry / portal Free registration NIH GDS Policy — open tier; controlled tier via dbGaP

The reference multi-omics cancer cohort: molecular profiles, clinical outcomes and whole-slide images for 33 cancer types, downloadable through the GDC portal and API.

11 000 patients 30 000 diagnostic + tissue WSIs 33 cancer types; ~11,000 patients with molecular data; diagnostic slides for most cases; matched clinical follow-up
Dataset site used by models: 7 Open card →

TCIA — The Cancer Imaging Archive

NCI Cancer Imaging Program; hosted by the University of Arkansas for Medical Sciences
Registry / portal Open download mostly CC BY 3.0/4.0 per collection; some restricted collections

The main public archive of de-identified cancer imaging, organised into collections by disease and modality; the source of most public radiology training data in oncology.

200 collections hundreds of collections, tens of thousands of patients; DICOM with linked clinical and sometimes genomic data
Dataset site used by models: 1 Open card →

Cards follow the cancer3.ai model-card standard: AI_MODEL_CARD_STANDARD.md. Corrections and new entries: contact the editorial team; every fact needs a public source.

This page is educational — it is not medical advice and does not replace consultation with an oncologist. Diagnostic and treatment decisions are made solely by specialist physicians.