Middle Ear
Glomus Tympanicum in an Asymptomatic 82-Year-Old Woman.
Matarazzo A, et al
In an 82-year-old woman with an incidentally discovered 3–4 mm Glasscock-Jackson type I glomus tympanicum of the right middle ear, five years of watchful waiting with serial clinical assessments and imaging demonstrated complete tumor stability, no significant growth, and no development of otologic …
Source →Unusual dual malignancy: basaloid squamous cell carcinoma arising from inverted papilloma with contralateral temporal bone carcinoma.
Eugine R, et al
A woman in her early 50s with a prior history of sinonasal inverted papilloma excisions 3 and 5 years earlier was diagnosed with a rare synchronous dual malignancy: sinonasal basaloid squamous cell carcinoma (BSCC) and a contralateral temporal bone non-keratinising squamous cell carcinoma, both with…
Source →Tympanic papillary adenoma (tympanic papilloma) in a cat - a case report.
Paździor-Czapula K, et al
Veterinary pathologists have documented a rare case of tympanic papillary adenoma in a 9-year-old cat, a tumor type with no direct equivalent in human pathology, which recurred within 17 months of surgical removal. The primary tumor was characterized histologically by papillary structures lined with…
Source →Hearing impairment following radiotherapy in patients with nasopharyngeal carcinoma (Review).
Liu L, et al
A comprehensive review published in Molecular and Clinical Oncology synthesizes current knowledge on radiotherapy-induced hearing loss in nasopharyngeal carcinoma (NPC), a malignant mucosal tumor endemic to southern China and Southeast Asia, for which radiotherapy combined with chemotherapy or targe…
Source →Diagnosis and Management of Middle Ear Neuroendocrine Tumour (MeNET).
Chomczyńska M, et al
A university otolaryngology centre presents a case series of five patients diagnosed with middle ear neuroendocrine tumours (MeNETs) between 2019 and 2025, underscoring the significant diagnostic challenge posed by this rare epithelial neoplasm whose symptoms — including conductive hearing loss, ota…
Source →Two-handed endoscopic lateral temporal bone resection for squamous cell carcinoma of external auditory canal.
Dosemane D, et al
A two-handed endoscopic lateral temporal bone resection achieved complete excision with histologically confirmed negative margins in a woman in her 20s with well-differentiated squamous cell carcinoma of the external auditory canal that occluded more than 75% of the canal lumen and involved cortical…
Source →Eosinophil Extracellular Traps in Health and Disease: From Host Defense to Chronic Inflammation.
Stojanovic B, et al
A comprehensive review concludes that eosinophil extracellular traps (EETs) — extracellular DNA-protein structures released by activated eosinophils via either cytolytic nuclear EETosis or rapid mitochondrial DNA release — are context-dependent effector structures with dual biological potential, cap…
Source →Watchful Waiting Compared With Immediate Antibiotics for Urban Aboriginal and Torres Strait Islander Children With Uncomplicated Acute Otitis Media (WATCH): A Non-Inferiority Randomised Controlled Trial.
Reath JS, et al
A randomised controlled trial of 263 urban Aboriginal and Torres Strait Islander children with acute otitis media failed to establish non-inferiority of watchful waiting compared with immediate oral antibiotics, as clinical resolution by Day 7 occurred in only 53.8% (57/106) of the watchful waiting …
Source →Epidemiology of Incidence and Mortality Due to Head and Neck Cancer in Poland in 2000 to 2022.
Zaborska P, et al
A comprehensive analysis of Polish National Cancer Registry data (2000–2022) reveals that the overall incidence of malignant head and neck cancers increased by more than 50% over the study period, with thyroid cancer showing the most dramatic rise of 226.9% and representing the most common head and …
Source →Primary glomangioma of the external auditory canal with extension to the middle ear and mastoid.
Khan ZM, et al
Surgeons have reported the first documented case of a primary glomangioma — a rare benign perivascular tumour — arising in the external auditory canal and extending into the middle ear, attic, mastoid antrum, and the tympanic opening of the Eustachian tube without bony erosion in a man in his 70s. T…
Source →Diagnosis of tympanic effusions using hyperspectral imaging to prevent unnecessary paracentesis procedures.
Gänzle M, et al
A new study published in BMC Medical Imaging demonstrates that hyperspectral imaging (HSI) can detect fluid behind the eardrum with 89% sensitivity, 78% specificity, and 83% accuracy, offering a promising non-invasive tool to confirm diagnoses of Otitis Media with Effusion (OME) in children. The res…
Source →Based on the middle ear negative pressure and multimodal data to construct and externally validate the predictive model for pediatric obstructive sleep apnea.
Zhu S, et al
Researchers developed a multimodal predictive model for pediatric obstructive sleep apnea (OSA) that achieves an AUC of 0.845 (95% CI: 0.813–0.878), with the addition of middle ear pressure (MEP) to the base model further improving the AUC by 0.022 (p < 0.05). The retrospective study enrolled 931 ch…
Source →Congenital Mastoid Cholesteatoma With Giant Intracranial Extension: A Case Report.
Novakovic N, et al
Surgeons have reported what appears to be the largest congenital mastoid cholesteatoma with supratentorial intracranial extension ever documented, measuring an extraordinary 71 × 59 × 89 mm in a 49-year-old woman who presented with left parietal bone softening, facial sensory disturbance, near-compl…
Source →Effect of adding biologic agents to disease-modifying anti-rheumatic drugs for refractory chronic suppurative otitis media: comparative outcomes and cytokine-driven mechanisms.
Wei B, et al
Adding biologic agents to disease-modifying anti-rheumatic drugs (DMARDs) significantly improves outcomes in refractory chronic suppurative otitis media (rCSOM), with combination therapy identified as an independent protective factor for otorrhea cessation at 12 weeks (OR=3.850, 95% CI: 1.101–13.466…
Source →Squamous Cell Carcinoma of the Temporal Bone Presenting With Facial Nerve Paralysis: A 25-Year Experience.
Bouzaher MH, et al
A 25-year retrospective study (January 1997 – December 2022) found that aggressive temporal bone resection with facial nerve sacrifice lateral to the geniculate ganglion, simultaneous free flap reconstruction, and adjuvant radiotherapy of at least 65 Gy achieved a disease-free survival of 81.3% and …
Source →