Cancer3.AIAI in Oncology › AI Models

AI in Oncology · AI Models

A researcher-grade catalog of AI models, datasets and open data needs in oncology — every card structured, sourced and dated.

Filter by task, data type, cancer, availability and regulatory status. Each card follows one model-card standard and links to Hugging Face, code, papers and the datasets it was trained or tested on. { } export JSON

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13 / 35 models Tick 2–4 models to compare them side by side.

BiomedBERT (PubMedBERT)

Microsoft Research · 2020
Foundation model Open weights Not applicable

BERT pretrained from scratch on PubMed abstracts and PMC full text with a biomedical vocabulary; the workhorse encoder for named-entity recognition, relation extraction and classification over oncology literature and reports.

220 044 downloads / month ♥ 335 updated 2023-11-06 Hugging Face Paper Open card →

BiomedCLIP

Microsoft Research · 2023
Foundation model Open weights Research use only

CLIP-style vision-language model pretrained on PMC-15M — 15 million figure–caption pairs from biomedical papers — with a PubMedBERT text tower and a ViT-B image tower; supports zero-shot classification and retrieval across pathology, radiology and more.

249 031 downloads / month ♥ 424 updated 2025-01-14 Hugging Face GitHub Paper Open card →

CONCH CONCH (v1)

Mahmood Lab, Brigham and Women's Hospital / Harvard Medical School · 2024
Foundation model Gated weights (licence click-through) Research use only

Vision-language foundation model for pathology: an image encoder and a text encoder trained together on 1.17 million histopathology image–caption pairs, enabling zero-shot classification and image–text retrieval without labelled slides.

58 735 downloads / month ♥ 204 updated 2024-05-05 gated Hugging Face GitHub Paper Open card →

ESM-2 / ESMFold

Meta AI (FAIR) · 2022
Foundation model Open weights Not applicable

Protein language models from 8 million to 15 billion parameters trained on UniRef sequences; embeddings power variant-effect and function prediction, and ESMFold predicts structure directly from a single sequence without MSAs.

1 303 383 downloads / month ♥ 89 updated 2023-03-21 Hugging Face GitHub Paper Open card →

Geneformer

Theodoris Lab (Gladstone Institutes / UCSF) · 2023
Foundation model Open weights Not applicable

Transformer pretrained on about 30 million single-cell transcriptomes (Genecorpus-30M) that learns gene-network context from ranked expression, enabling few-shot prediction of gene dosage effects, cell states and candidate therapeutic targets.

1 698 downloads / month ♥ 311 updated 2026-05-26 Hugging Face Paper Open card →

H-optimus-0

Bioptimus · 2024
Foundation model Gated weights (licence click-through) Research use only

1.1-billion-parameter ViT-g/14 pathology encoder trained on more than 500,000 H&E slides (hundreds of millions of tiles), released under Apache-2.0 — one of the few large pathology foundation models with a permissive licence.

80 579 downloads / month ♥ 92 updated 2025-12-12 gated Hugging Face Open card →

Prov-GigaPath

Microsoft Research / Providence Health / University of Washington · 2024
Foundation model Gated weights (licence click-through) Research use only

Whole-slide foundation model with 1.3 billion parameters, pretrained on 1.3 billion tiles from 171,189 slides of real-world clinical data; pairs a DINOv2 tile encoder with a LongNet slide encoder that reasons over an entire slide.

45 031 downloads / month ♥ 189 updated 2026-08-07 gated Hugging Face GitHub Paper Open card →

Virchow2

Paige / Memorial Sloan Kettering Cancer Center · 2024
Foundation model Gated weights (licence click-through) Research use only

Successor to Virchow: ViT-H/14 pretrained on 3.1 million whole-slide images from about 225,000 patients across 45 countries, at mixed magnifications (5×–40×), with pathology-specific augmentations.

110 111 downloads / month ♥ 151 updated 2024-10-26 gated Hugging Face Paper Open card →

UNI UNI (v1)

Mahmood Lab, Brigham and Women's Hospital / Harvard Medical School · 2024
Foundation model Gated weights (licence click-through) Research use only

General-purpose self-supervised vision encoder for H&E histopathology tiles, pretrained on more than 100 million tiles from over 100,000 whole-slide images; the reference foundation model for pathology feature extraction.

40 388 downloads / month ♥ 372 updated 2025-03-06 gated Hugging Face GitHub Paper Open card →

Virchow Virchow (v1)

Paige / Memorial Sloan Kettering Cancer Center · 2024
Foundation model Gated weights (licence click-through) Research use only

632-million-parameter vision transformer pretrained on 1.5 million whole-slide images from about 100,000 patients — the largest pathology pretraining set at its release — and used to build a pan-cancer detection model covering 17 cancer types, including rare ones.

7 616 downloads / month ♥ 76 updated 2024-09-03 gated Hugging Face Paper Open card →

Cards follow the cancer3.ai model-card standard: AI_MODEL_CARD_STANDARD.md. Corrections and new entries: contact the editorial team; every fact needs a public source.

This page is educational — it is not medical advice and does not replace consultation with an oncologist. Diagnostic and treatment decisions are made solely by specialist physicians.