Neutrophils in cancer

★ 5.5 / 10 Nature Reviews Cancer 2026-09-07

A comprehensive review in Nature Reviews Cancer examines the context-dependent pro-tumour and antitumour roles of neutrophils across cancer types, including their contributions to tumour progression and metastasis. Diehl, Basto et al. draw parallels between neutrophil functions in cancer and non-cancer inflammatory settings to clarify the mechanisms underlying neutrophil plasticity. The review highlights emerging therapeutic strategies aimed at targeting or reprogramming neutrophil biology to enhance antitumour immunity.

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