Scientists find breast cancer cells hiding behind protective “shields”

Researchers have mapped breast tumors at high resolution and identified hidden pockets of dormant cancer cells that may explain cancer recurrence after treatment. These quiescent cells can effectively hibernate, evading chemotherapy that targets rapidly dividing cells, and reactivate at a later time. The team discovered that dormant cells are frequently surrounded by immune cells and connective tissue cells that appear to form a protective microenvironment shielding them from both treatment and immune surveillance.