A clinically-oriented foundation model for intraoperative pathology

★ 7.5 / 10 AI Nature Medicine 2026-09-10

CRISP, a vision-based foundation model trained exclusively on frozen section slides, outperformed existing foundation models in supporting intraoperative treatment decisions, according to its authors. Validation included a prospective patient cohort. Specialising in frozen sections is intended to address the artefacts and time constraints specific to intraoperative diagnostics. The paper describes a research tool; it is not an approved medical device and does not change the standard of care.

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