{"architecture":{"family":"convolutional image encoder + transformer over views","input":"four-view screening mammogram (+ optional risk factors)","output":"risk at years 1\u20135","pretraining":"supervised on MGH screening mammograms with follow-up"},"article":null,"cancer_slugs":["invasive-breast-carcinoma"],"category":"radiology","confidence":"medium","datasets":[],"developer":"MIT Jameel Clinic / Massachusetts General Hospital","evaluation":[{"benchmark":"MGH test / Karolinska / CGMH","external":true,"metric":"C-index (5-year risk)","source":"https://www.science.org/doi/10.1126/scitranslmed.aba4373","value":"higher than Tyrer-Cuzick v8 in all three (paper)"}],"hf":null,"kind":"task-model","license":"MIT","limitations":"- Vendor-specific mammography systems in training; calibration must be checked per site.\n- Risk model, not a lesion detector.","links":{"demo":null,"docs":null,"doi":"10.1126/scitranslmed.aba4373","github":"https://github.com/yala/Mirai","huggingface":null,"paper":"https://www.science.org/doi/10.1126/scitranslmed.aba4373","pmid":null},"modalities":["mammography"],"name":"Mirai","notable_uses":"","openness":"open-weights","regulatory":{"intended_use_en":"Research.","intended_use_pl":"Badania.","source_url":"https://github.com/yala/Mirai","status":"research-only"},"regulatory_status":"research-only","release_date":"2021-01-27","run_snippet":"","settings":["screening"],"slug":"mirai","sources":[{"label":"Yala A et al. Toward robust mammography-based models for breast cancer risk. Sci Transl Med 2021","url":"https://www.science.org/doi/10.1126/scitranslmed.aba4373"}],"summary":"Mammography-based model predicting five-year breast cancer risk from the four standard screening views, designed to be robust across hospitals and to work with or without clinical risk factors.","tasks":["risk-prediction","screening"],"training":{"institutions":"MGH (USA); Karolinska (SE); CGMH (TW)","summary_en":"Screening mammograms from Massachusetts General Hospital with cancer follow-up; external validation at Karolinska (Sweden) and Chang Gung Memorial Hospital (Taiwan).","summary_pl":"Mammografie przesiewowe z Massachusetts General Hospital z obserwacj\u0105; walidacja zewn\u0119trzna w Karolinska (Szwecja) i Chang Gung Memorial Hospital (Tajwan)."},"updated_at":"2026-09-05T22:26:01.518085","url":"/ai-oncology/models/mirai","usage":{"library":"PyTorch (repo)","notes_en":"Weights and inference code on GitHub; requires DICOM preprocessing described in the repo."},"verified_at":"2026-09-05T22:26:01.517810","verified_by":"editorial","version":null,"what_it_does":"Outputs risk at years 1\u20135 from a screening mammogram; the paper compares it with the Tyrer-Cuzick model and reports higher discrimination on internal and external cohorts."}