{"count":1,"items":[{"article":null,"cancer_slugs":["pan-cancer"],"category":"drug-discovery","confidence":"medium","developer":"Zitnik Lab, Harvard Medical School","hf":null,"kind":"task-model","license":"MIT","links":{"demo":null,"docs":null,"doi":"10.1038/s41591-024-03233-x","github":"https://github.com/mims-harvard/TxGNN","huggingface":null,"paper":"https://www.nature.com/articles/s41591-024-03233-x","pmid":null},"modalities":["molecules","literature"],"name":"TxGNN","openness":"open-weights","regulatory_status":"research-only","release_date":"2024-09-25","settings":["drug-discovery"],"slug":"txgnn","summary":"Graph neural network for zero-shot drug repurposing that scores drug\u2013disease indications and contraindications over a medical knowledge graph of 17,080 diseases, including ones with no approved treatment.","tasks":["drug-repurposing","drug-discovery"],"url":"/ai-oncology/models/txgnn","verified_at":"2026-09-05T22:26:01.078860","version":null}],"standard":"https://cancer3.ai/docs/ai-model-card","vocab":{"confidence":["high","medium","low"],"dataset_access":["open","registration","dua","controlled","commercial"],"dataset_kinds":["dataset","registry","benchmark","biobank","corpus"],"formats":["SVS","TIFF","NDPI","DICOM","NIfTI","PNG","JPEG","CSV","TSV","JSON","Parquet","FASTQ","BAM","VCF","MAF","h5ad","PDB","mmCIF","text","other"],"kinds":["foundation","task-model","tool","framework","product"],"link_roles":["pretraining","training","finetuning","evaluation","benchmark"],"modalities":["histopathology","radiology-ct","radiology-mri","radiology-xray","mammography","pet","ultrasound","dermoscopy","endoscopy","genomics","transcriptomics","single-cell","proteomics","protein-sequence","molecules","clinical-text","literature","ehr","multimodal","immunopeptidomics"],"need_status":["open","in-progress","solved"],"openness":["open-weights","gated-weights","api-only","closed"],"regulatory":["research-only","fda-cleared","fda-de-novo","fda-pma","ce-marked","ce-ivdr","not-applicable"],"settings":["basic-research","screening","diagnosis","prognosis","treatment-planning","treatment-response","drug-discovery","clinical-trials","education","vaccine-design","immunotherapy"],"tasks":["feature-extraction","classification","segmentation","detection","screening","risk-prediction","prognosis","treatment-response","survival-analysis","image-text-retrieval","report-generation","question-answering","information-extraction","clinical-trial-matching","protein-structure","variant-effect","gene-expression","single-cell","drug-discovery","drug-repurposing","peptide-mhc-binding","antigen-presentation","neoantigen-prioritisation"]}}