{"access":"registration","annotations":"Per-case clinical data (stage, grade, vital status, survival), somatic mutations (MAF), copy number, RNA-seq expression, methylation, miRNA, and slide images; slide-level labels are the pathology diagnosis, not region annotations.","article":null,"cancer_slugs":["pan-cancer"],"details":"WHAT IS IN IT.\n- Harmonised genomic data re-processed by the GDC against GRCh38.\n- Diagnostic (FFPE) and frozen-tissue slides in Aperio SVS format.\n- Clinical and biospecimen supplements; cBioPortal offers a browsing front end.\nHOW TO GET IT.\n- Open-access files download without an account through the portal or the gdc-client.\n- Controlled data require dbGaP authorisation via an institutional signing official.\nKNOWN PITFALLS.\n- Slide scanners, sites and batch effects vary; several pathology foundation models pretrained on TCGA, so it is not an external test set for them.\n- Survival follow-up is short for some projects.","doi":null,"formats":["SVS","MAF","VCF","BAM","TSV","JSON"],"hf":null,"huggingface":null,"kind":"registry","license":"NIH GDS Policy \u2014 open tier; controlled tier via dbGaP","modalities":["genomics","transcriptomics","histopathology","radiology-ct","radiology-mri"],"models":[{"name":"UNI","note":"subtyping and biomarker tasks drawn from TCGA cohorts","role":"evaluation","slug":"uni"},{"name":"CONCH","note":"","role":"evaluation","slug":"conch"},{"name":"Prov-GigaPath","note":"","role":"evaluation","slug":"prov-gigapath"},{"name":"Phikon-v2","note":"part of PANCAN-XL \u2014 not a valid external test set","role":"pretraining","slug":"phikon-v2"},{"name":"CHIEF","note":"","role":"training","slug":"chief"},{"name":"H-optimus-0","note":"","role":"evaluation","slug":"h-optimus-0"},{"name":"Phikon-v2","note":"","role":"training","slug":"phikon-v2"}],"name":"TCGA \u2014 The Cancer Genome Atlas (via NCI Genomic Data Commons)","page":"/ai-oncology/datasets/tcga","provider":"NCI / NHGRI; hosted by the Genomic Data Commons","size":{"items":30000,"notes_en":"33 cancer types; ~11,000 patients with molecular data; diagnostic slides for most cases; matched clinical follow-up","notes_pl":"33 typy nowotwor\u00f3w; ok. 11 000 pacjent\u00f3w z danymi molekularnymi; preparaty diagnostyczne dla wi\u0119kszo\u015bci przypadk\u00f3w; dopasowana obserwacja kliniczna","patients":11000,"unit":"diagnostic + tissue WSIs"},"slug":"tcga","sources":[{"label":"GDC Data Portal","url":"https://portal.gdc.cancer.gov/"},{"label":"NCI \u2014 The Cancer Genome Atlas Program","url":"https://www.cancer.gov/ccg/research/genome-sequencing/tcga"}],"summary":"The reference multi-omics cancer cohort: molecular profiles, clinical outcomes and whole-slide images for 33 cancer types, downloadable through the GDC portal and API.","tasks":["classification","prognosis","survival-analysis","variant-effect","gene-expression"],"url":"https://portal.gdc.cancer.gov/","verified_at":"2026-09-05T22:25:58.814252"}